STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRG22404.1Methylmalonyl-CoA carboxyltransferase 12S subunit. (535 aa)    
Predicted Functional Partners:
accA1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain.
 0.999
echA8
Putative enoyl-CoA hydratase echA8.
 
 0.994
acdA_1
Acyl-CoA dehydrogenase.
 
 0.994
yngG
Hydroxymethylglutaryl-CoA lyase YngG.
 0.985
accC
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.975
fadJ
Fatty acid oxidation complex subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.940
fadN
Putative 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.940
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
 
 0.940
lly
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.924
pdhB_2
Pyruvate dehydrogenase E1 component subunit beta.
  
 
 0.921
Your Current Organism:
Berkiella aquae
NCBI taxonomy Id: 295108
Other names: C. Berkiella aquae, Candidatus Berkiella aquae, Coxiellaceae bacterium HT99, Legionella-like amoebal pathogen HT99
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.