KRG21956.1 protein (Berkiella aquae) - STRING interaction network

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KRG21956.1

Putative acyl-CoA thioester hydrolase. (134 aa)

Predicted Functional Partners:

fadJ

0.894

fadN

0.894

yciB

0.689

etfA

0.662

acs

0.629

echA8

0.628

etfB

0.600

sucC

0.591

adh

0.552

ftsI_1

0.544

Your Current Organism:

Berkiella aquae

NCBI taxonomy Id: 295108
Other names: C. Berkiella aquae, Candidatus Berkiella aquae, Coxiellaceae bacterium HT99, Legionella-like amoebal pathogen HT99

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRG21956.1	acs	HT99x_01150	HT99x_02338	Putative acyl-CoA thioester hydrolase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.629
KRG21956.1	adh	HT99x_01150	HT99x_01296	Putative acyl-CoA thioester hydrolase.	NADP-dependent isopropanol dehydrogenase.	0.552
KRG21956.1	echA8	HT99x_01150	HT99x_00825	Putative acyl-CoA thioester hydrolase.	Putative enoyl-CoA hydratase echA8.	0.628
KRG21956.1	etfA	HT99x_01150	HT99x_00799	Putative acyl-CoA thioester hydrolase.	Electron transfer flavoprotein subunit alpha.	0.662
KRG21956.1	etfB	HT99x_01150	HT99x_00798	Putative acyl-CoA thioester hydrolase.	Electron transfer flavoprotein subunit beta.	0.600
KRG21956.1	fadJ	HT99x_01150	HT99x_00354	Putative acyl-CoA thioester hydrolase.	Fatty acid oxidation complex subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.894
KRG21956.1	fadN	HT99x_01150	HT99x_00355	Putative acyl-CoA thioester hydrolase.	Putative 3-hydroxyacyl-CoA dehydrogenase.	0.894
KRG21956.1	ftsI_1	HT99x_01150	HT99x_01151	Putative acyl-CoA thioester hydrolase.	Peptidoglycan synthase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.	0.544
KRG21956.1	sucC	HT99x_01150	HT99x_00127	Putative acyl-CoA thioester hydrolase.	Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.591
KRG21956.1	yciB	HT99x_01150	HT99x_00135	Putative acyl-CoA thioester hydrolase.	Intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.	0.689
acs	KRG21956.1	HT99x_02338	HT99x_01150	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Putative acyl-CoA thioester hydrolase.	0.629
acs	adh	HT99x_02338	HT99x_01296	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	NADP-dependent isopropanol dehydrogenase.	0.629
acs	echA8	HT99x_02338	HT99x_00825	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Putative enoyl-CoA hydratase echA8.	0.792
acs	fadJ	HT99x_02338	HT99x_00354	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Fatty acid oxidation complex subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.972
acs	fadN	HT99x_02338	HT99x_00355	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Putative 3-hydroxyacyl-CoA dehydrogenase.	0.972
acs	sucC	HT99x_02338	HT99x_00127	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.708
adh	KRG21956.1	HT99x_01296	HT99x_01150	NADP-dependent isopropanol dehydrogenase.	Putative acyl-CoA thioester hydrolase.	0.552
adh	acs	HT99x_01296	HT99x_02338	NADP-dependent isopropanol dehydrogenase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.629
adh	fadJ	HT99x_01296	HT99x_00354	NADP-dependent isopropanol dehydrogenase.	Fatty acid oxidation complex subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.668
adh	fadN	HT99x_01296	HT99x_00355	NADP-dependent isopropanol dehydrogenase.	Putative 3-hydroxyacyl-CoA dehydrogenase.	0.668