Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRG21305.1Hypothetical protein. (4642 aa)    
Predicted Functional Partners:
apxIB_1
Toxin RTX-I translocation ATP-binding protein.
 
 
 0.874
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.861
guaA_2
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
  0.830
KRG22828.1
Hypothetical protein.
 
 
0.828
KRG22830.1
Hypothetical protein.
 
 
0.828
KRG21322.1
Hypothetical protein.
 
 
 0.809
prsE_1
Type I secretion system membrane fusion protein PrsE.
 
 
  0.785
prsE_2
Type I secretion system membrane fusion protein PrsE.
 
 
  0.783
prsE_3
Type I secretion system membrane fusion protein PrsE.
 
 
  0.783
bepC
Outer membrane efflux protein BepC precursor.
 
 
  0.767
Your Current Organism:
Berkiella aquae
NCBI taxonomy Id: 295108
Other names: C. Berkiella aquae, Candidatus Berkiella aquae, Coxiellaceae bacterium HT99, Legionella-like amoebal pathogen HT99
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