node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroC | aroF | HT99x_02541 | HT99x_00376 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.830 |
aroC | ilvE | HT99x_02541 | HT99x_01833 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.716 |
aroC | pabA | HT99x_02541 | HT99x_00347 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate synthase component 2. | 0.865 |
aroC | pabB | HT99x_02541 | HT99x_01532 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate synthase component 1. | 0.892 |
aroC | trpA | HT99x_02541 | HT99x_01483 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.771 |
aroC | trpB | HT99x_02541 | HT99x_01484 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.561 |
aroC | trpC | HT99x_02541 | HT99x_01485 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan biosynthesis protein TrpCF; Belongs to the TrpF family. | 0.882 |
aroC | trpGD | HT99x_02541 | HT99x_01486 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Bifunctional protein TrpGD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.822 |
aroF | aroC | HT99x_00376 | HT99x_02541 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.830 |
aroF | ilvE | HT99x_00376 | HT99x_01833 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.622 |
aroF | pabA | HT99x_00376 | HT99x_00347 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Aminodeoxychorismate synthase component 2. | 0.658 |
aroF | pabB | HT99x_00376 | HT99x_01532 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Aminodeoxychorismate synthase component 1. | 0.718 |
aroF | trpGD | HT99x_00376 | HT99x_01486 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Bifunctional protein TrpGD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.633 |
hisA | hisE | HT99x_01093 | HT99x_01091 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.999 |
hisA | pabA | HT99x_01093 | HT99x_00347 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Aminodeoxychorismate synthase component 2. | 0.558 |
hisA | trpB | HT99x_01093 | HT99x_01484 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.750 |
hisA | trpC | HT99x_01093 | HT99x_01485 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Tryptophan biosynthesis protein TrpCF; Belongs to the TrpF family. | 0.907 |
hisA | trpGD | HT99x_01093 | HT99x_01486 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Bifunctional protein TrpGD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.750 |
hisE | hisA | HT99x_01091 | HT99x_01093 | Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.999 |
hisE | ilvE | HT99x_01091 | HT99x_01833 | Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.639 |