STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
acsAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (618 aa)    
Predicted Functional Partners:
fadJ
Fatty acid oxidation complex subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.972
fadN
Putative 3-hydroxyacyl-CoA dehydrogenase.
  
 0.972
pta
Phosphate acetyltransferase.
  
 
 0.935
KRG20878.1
Long-chain-fatty-acid--AMP ligase FadD29.
 
 
0.919
korA
2-oxoglutarate oxidoreductase subunit KorA.
  
 
 0.904
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.899
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 0.899
fadD
Long-chain-fatty-acid--CoA ligase.
 
0.867
thlA_2
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.863
pdhB_2
Pyruvate dehydrogenase E1 component subunit beta.
  
 
 0.853
Your Current Organism:
Berkiella aquae
NCBI taxonomy Id: 295108
Other names: C. Berkiella aquae, Candidatus Berkiella aquae, Coxiellaceae bacterium HT99, Legionella-like amoebal pathogen HT99
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