node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APJ09065.1 | APJ09066.1 | BLA32_04185 | BLA32_04190 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.826 |
APJ09065.1 | pfp | BLA32_04185 | BLA32_04180 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.826 |
APJ09065.1 | queA | BLA32_04185 | BLA32_04175 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.655 |
APJ09065.1 | ruvA | BLA32_04185 | BLA32_04165 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.522 |
APJ09065.1 | ruvB | BLA32_04185 | BLA32_04170 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.655 |
APJ09066.1 | APJ09065.1 | BLA32_04190 | BLA32_04185 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.826 |
APJ09066.1 | nadE | BLA32_04190 | BLA32_01665 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. | 0.445 |
APJ09066.1 | pfp | BLA32_04190 | BLA32_04180 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.846 |
APJ09066.1 | polA | BLA32_04190 | BLA32_01530 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.737 |
APJ09066.1 | queA | BLA32_04190 | BLA32_04175 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.676 |
APJ09066.1 | ruvA | BLA32_04190 | BLA32_04165 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.529 |
APJ09066.1 | ruvB | BLA32_04190 | BLA32_04170 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.655 |
APJ09066.1 | truB | BLA32_04190 | BLA32_00205 | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA pseudouridine(55) synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.466 |
nadE | APJ09066.1 | BLA32_01665 | BLA32_04190 | NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. | RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.445 |
nadE | polA | BLA32_01665 | BLA32_01530 | NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.695 |
nadE | queA | BLA32_01665 | BLA32_04175 | NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.629 |
nadE | ruvA | BLA32_01665 | BLA32_04165 | NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.580 |
nadE | ruvB | BLA32_01665 | BLA32_04170 | NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.614 |
nadE | tgt | BLA32_01665 | BLA32_00175 | NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. | tRNA guanosine(34) transglycosylase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...] | 0.546 |
nadE | truB | BLA32_01665 | BLA32_00205 | NAD(+) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. | tRNA pseudouridine(55) synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.498 |