STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribB3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (376 aa)    
Predicted Functional Partners:
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.999
SHN08596.1
Riboflavin synthase alpha chain.
 0.999
SHL58676.1
Signal transduction histidine kinase.
  
 0.960
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.960
folE
GTP cyclohydrolase I.
 
 
 0.957
SHL53364.1
Hypothetical protein.
  
 0.954
SHM43157.1
PAS domain S-box-containing protein.
  
 0.953
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase.
 
 
 0.933
SHL54460.1
Two-component system, chemotaxis family, CheB/CheR fusion protein.
    
 0.930
Your Current Organism:
Flavobacterium pectinovorum
NCBI taxonomy Id: 29533
Other names: ATCC 19366, CIP 104742, Cytophaga pectinovora, DSM 6368, Empedobacter pectinovorum, F. pectinovorum, Flavibacterium pectinovorum, IFO 15945, JCM 8518, LMG 4031, LMG:4031, NBRC 15945, NCIMB 9059, strain number 81 Dorey
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.