node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHM55665.1 | SHN05230.1 | SAMN05444387_2806 | SAMN05444387_3857 | Putative hydrolase of the HAD superfamily. | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.438 |
SHM55665.1 | SHN08596.1 | SAMN05444387_2806 | SAMN05444387_4025 | Putative hydrolase of the HAD superfamily. | Riboflavin synthase alpha chain. | 0.452 |
SHM55665.1 | ribD | SAMN05444387_2806 | SAMN05444387_2805 | Putative hydrolase of the HAD superfamily. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.975 |
SHM55665.1 | ribH | SAMN05444387_2806 | SAMN05444387_3173 | Putative hydrolase of the HAD superfamily. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.808 |
SHN05230.1 | SHM55665.1 | SAMN05444387_3857 | SAMN05444387_2806 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Putative hydrolase of the HAD superfamily. | 0.438 |
SHN05230.1 | SHN08596.1 | SAMN05444387_3857 | SAMN05444387_4025 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Riboflavin synthase alpha chain. | 0.947 |
SHN05230.1 | metK | SAMN05444387_3857 | SAMN05444387_2037 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.483 |
SHN05230.1 | ribB | SAMN05444387_3857 | SAMN05444387_0121 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.902 |
SHN05230.1 | ribD | SAMN05444387_3857 | SAMN05444387_2805 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.890 |
SHN05230.1 | ribH | SAMN05444387_3857 | SAMN05444387_3173 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.961 |
SHN08596.1 | SHM55665.1 | SAMN05444387_4025 | SAMN05444387_2806 | Riboflavin synthase alpha chain. | Putative hydrolase of the HAD superfamily. | 0.452 |
SHN08596.1 | SHN05230.1 | SAMN05444387_4025 | SAMN05444387_3857 | Riboflavin synthase alpha chain. | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.947 |
SHN08596.1 | folP | SAMN05444387_4025 | SAMN05444387_0679 | Riboflavin synthase alpha chain. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.473 |
SHN08596.1 | ribB | SAMN05444387_4025 | SAMN05444387_0121 | Riboflavin synthase alpha chain. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
SHN08596.1 | ribD | SAMN05444387_4025 | SAMN05444387_2805 | Riboflavin synthase alpha chain. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
SHN08596.1 | ribH | SAMN05444387_4025 | SAMN05444387_3173 | Riboflavin synthase alpha chain. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.998 |
folP | SHN08596.1 | SAMN05444387_0679 | SAMN05444387_4025 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Riboflavin synthase alpha chain. | 0.473 |
folP | metK | SAMN05444387_0679 | SAMN05444387_2037 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.534 |
folP | ribB | SAMN05444387_0679 | SAMN05444387_0121 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.667 |
folP | ribD | SAMN05444387_0679 | SAMN05444387_2805 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.666 |