STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHL26908.1Succinate dehydrogenase / fumarate reductase cytochrome b subunit. (221 aa)    
Predicted Functional Partners:
SHL26875.1
Succinate dehydrogenase subunit A.
 
 
 0.998
SHL26817.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
 
 
 0.995
SHL79570.1
Succinate dehydrogenase subunit A.
 
 
 0.974
SHL79596.1
Succinate dehydrogenase / fumarate reductase iron-sulfur subunit.
 
 
 0.972
SHL32210.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.923
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.921
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.921
SHL81670.1
Fumarylacetoacetate hydrolase.
    
  0.906
SHM18993.1
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
    
  0.762
SHM39178.1
Glycine/D-amino acid oxidase.
   
  
 0.695
Your Current Organism:
Flavobacterium saccharophilum
NCBI taxonomy Id: 29534
Other names: ATCC 49530, CIP 104743, Cytophaga saccharophila, F. saccharophilum, IFO 15944, JCM 8520, LMG 8384, LMG:8384, NBRC 15944, NCIMB 2072, strain 024 Agbo and Moss
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