node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHL50344.1 | SHL50437.1 | SAMN05444366_0937 | SAMN05444366_0940 | O-acetylhomoserine sulfhydrylase. | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | 0.991 |
SHL50344.1 | SHL86931.1 | SAMN05444366_0937 | SAMN05444366_1854 | O-acetylhomoserine sulfhydrylase. | Cystathionine beta-synthase. | 0.934 |
SHL50344.1 | SHL88063.1 | SAMN05444366_0937 | SAMN05444366_1896 | O-acetylhomoserine sulfhydrylase. | Serine O-acetyltransferase. | 0.904 |
SHL50344.1 | SHL88088.1 | SAMN05444366_0937 | SAMN05444366_1897 | O-acetylhomoserine sulfhydrylase. | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.527 |
SHL50344.1 | SHM72363.1 | SAMN05444366_0937 | SAMN05444366_3914 | O-acetylhomoserine sulfhydrylase. | Cystathionine beta-synthase. | 0.948 |
SHL50344.1 | cysS | SAMN05444366_0937 | SAMN05444366_4312 | O-acetylhomoserine sulfhydrylase. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.446 |
SHL50344.1 | ilvA | SAMN05444366_0937 | SAMN05444366_3938 | O-acetylhomoserine sulfhydrylase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.909 |
SHL50344.1 | thrB | SAMN05444366_0937 | SAMN05444366_1830 | O-acetylhomoserine sulfhydrylase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.902 |
SHL50437.1 | SHL50344.1 | SAMN05444366_0940 | SAMN05444366_0937 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | O-acetylhomoserine sulfhydrylase. | 0.991 |
SHL50437.1 | SHL86931.1 | SAMN05444366_0940 | SAMN05444366_1854 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Cystathionine beta-synthase. | 0.823 |
SHL50437.1 | SHL88063.1 | SAMN05444366_0940 | SAMN05444366_1896 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Serine O-acetyltransferase. | 0.880 |
SHL50437.1 | SHL88088.1 | SAMN05444366_0940 | SAMN05444366_1897 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.823 |
SHL50437.1 | SHM10844.1 | SAMN05444366_0940 | SAMN05444366_2375 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.815 |
SHL50437.1 | SHM72363.1 | SAMN05444366_0940 | SAMN05444366_3914 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Cystathionine beta-synthase. | 0.944 |
SHL50437.1 | cysS | SAMN05444366_0940 | SAMN05444366_4312 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.724 |
SHL50437.1 | glyA | SAMN05444366_0940 | SAMN05444366_1655 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.870 |
SHL50437.1 | ilvA | SAMN05444366_0940 | SAMN05444366_3938 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.949 |
SHL50437.1 | thrB | SAMN05444366_0940 | SAMN05444366_1830 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.991 |
SHL86931.1 | SHL50344.1 | SAMN05444366_1854 | SAMN05444366_0937 | Cystathionine beta-synthase. | O-acetylhomoserine sulfhydrylase. | 0.934 |
SHL86931.1 | SHL50437.1 | SAMN05444366_1854 | SAMN05444366_0940 | Cystathionine beta-synthase. | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | 0.823 |