STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM78940.1Phosphoserine phosphatase. (409 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.974
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.970
hisI
phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.961
SHL50368.1
Homoserine dehydrogenase.
  
 
 0.957
SHL50437.1
Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
  
 
 0.957
SHL50475.1
Aspartate kinase.
  
 
 0.957
SHM72363.1
Cystathionine beta-synthase.
    
 0.943
SHL86291.1
Aspartate kinase.
  
 
 0.937
trpF
Phosphoribosylanthranilate isomerase; Manually curated; Belongs to the TrpF family.
  
 
 0.935
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 
 0.935
Your Current Organism:
Flavobacterium saccharophilum
NCBI taxonomy Id: 29534
Other names: ATCC 49530, CIP 104743, Cytophaga saccharophila, F. saccharophilum, IFO 15944, JCM 8520, LMG 8384, LMG:8384, NBRC 15944, NCIMB 2072, strain 024 Agbo and Moss
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