| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acsA | alkH | FLB_16840 | FLB_08860 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.930 |
| acsA | betB | FLB_16840 | FLB_22330 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | NAD/NADP-dependent betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.930 |
| acsA | fadN | FLB_16840 | FLB_13730 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Putative 3-hydroxyacyl-CoA dehydrogenase. | 0.972 |
| acsA | fumB | FLB_16840 | FLB_20430 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.592 |
| acsA | gbsA | FLB_16840 | FLB_05970 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Betaine aldehyde dehydrogenase. | 0.786 |
| acsA | gltB_2 | FLB_16840 | FLB_01200 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Ferredoxin-dependent glutamate synthase 1. | 0.687 |
| acsA | maeB | FLB_16840 | FLB_25760 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | NADP-dependent malic enzyme. | 0.861 |
| acsA | rocA_1 | FLB_16840 | FLB_05960 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 1-pyrroline-5-carboxylate dehydrogenase. | 0.534 |
| acsA | sad | FLB_16840 | FLB_05980 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Succinate semialdehyde dehydrogenase Sad. | 0.676 |
| alkH | acsA | FLB_08860 | FLB_16840 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.930 |
| alkH | betB | FLB_08860 | FLB_22330 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | NAD/NADP-dependent betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.895 |
| alkH | deoC1 | FLB_08860 | FLB_25810 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Deoxyribose-phosphate aldolase 1. | 0.689 |
| alkH | fadN | FLB_08860 | FLB_13730 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Putative 3-hydroxyacyl-CoA dehydrogenase. | 0.684 |
| alkH | fumB | FLB_08860 | FLB_20430 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.724 |
| alkH | gbsA | FLB_08860 | FLB_05970 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Betaine aldehyde dehydrogenase. | 0.772 |
| alkH | gltB_2 | FLB_08860 | FLB_01200 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Ferredoxin-dependent glutamate synthase 1. | 0.863 |
| alkH | maeB | FLB_08860 | FLB_25760 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | NADP-dependent malic enzyme. | 0.724 |
| betB | acsA | FLB_22330 | FLB_16840 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.930 |
| betB | alkH | FLB_22330 | FLB_08860 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.895 |
| betB | deoC1 | FLB_22330 | FLB_25810 | NAD/NADP-dependent betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Deoxyribose-phosphate aldolase 1. | 0.689 |