| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB | pyrB | FLB_06280 | FLB_10240 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrD | FLB_06280 | FLB_01610 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.956 |
| carB | pyrE | FLB_06280 | FLB_08210 | Carbamoyl-phosphate synthase large chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.912 |
| carB | pyrF | FLB_06280 | FLB_07610 | Carbamoyl-phosphate synthase large chain. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.903 |
| carB | pyrR_1 | FLB_06280 | FLB_04990 | Carbamoyl-phosphate synthase large chain. | Bifunctional protein PyrR. | 0.787 |
| carB | pyrR_2 | FLB_06280 | FLB_10230 | Carbamoyl-phosphate synthase large chain. | Bifunctional protein PyrR. | 0.787 |
| carB | upp | FLB_06280 | FLB_21220 | Carbamoyl-phosphate synthase large chain. | Uracil phosphoribosyltransferase. | 0.472 |
| pyrB | carB | FLB_10240 | FLB_06280 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl-phosphate synthase large chain. | 0.999 |
| pyrB | pyrD | FLB_10240 | FLB_01610 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.946 |
| pyrB | pyrE | FLB_10240 | FLB_08210 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.920 |
| pyrB | pyrF | FLB_10240 | FLB_07610 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.903 |
| pyrB | pyrH | FLB_10240 | FLB_18910 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.427 |
| pyrB | pyrR_1 | FLB_10240 | FLB_04990 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Bifunctional protein PyrR. | 0.968 |
| pyrB | pyrR_2 | FLB_10240 | FLB_10230 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Bifunctional protein PyrR. | 0.994 |
| pyrB | upp | FLB_10240 | FLB_21220 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uracil phosphoribosyltransferase. | 0.669 |
| pyrD | carB | FLB_01610 | FLB_06280 | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Carbamoyl-phosphate synthase large chain. | 0.956 |
| pyrD | pyrB | FLB_01610 | FLB_10240 | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.946 |
| pyrD | pyrE | FLB_01610 | FLB_08210 | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.995 |
| pyrD | pyrF | FLB_01610 | FLB_07610 | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.940 |
| pyrD | pyrR_1 | FLB_01610 | FLB_04990 | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Bifunctional protein PyrR. | 0.777 |