STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (215 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
 
 
 0.998
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 0.995
prs
Ribose-phosphate pyrophosphokinase.
  
 
 0.922
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.920
carB
Carbamoyl-phosphate synthase large chain.
  
 
 0.912
allB
Allantoinase.
 
 
 0.899
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
  
  
 0.893
pyrC
Dihydroorotase.
 
 
 0.878
pyrR_1
Bifunctional protein PyrR.
  
 
 0.849
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.849
Your Current Organism:
Flavobacterium succinicans
NCBI taxonomy Id: 29536
Other names: CIP 104744, Cytophaga succinicans, DSM 4002, F. succinicans, Flavobacterium sp. DD5b, Flexibacter succinicans, IFO 14905, JCM 21151, LMG 10402, LMG:10402, NBRC 14905, NCIMB 2277, strain 8
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