STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mccBCystathionine gamma-lyase. (402 aa)    
Predicted Functional Partners:
cbs_2
Putative cystathionine beta-synthase.
 
 0.958
metX
Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
 
 0.911
thrA_2
Bifunctional aspartokinase/homoserine dehydrogenase 1.
 
 
 0.900
metH_1
Methionine synthase.
  
 
 0.862
thrA_1
Bifunctional aspartokinase/homoserine dehydrogenase 1.
 
 
 0.840
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.826
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 0.825
cbs_1
Putative cystathionine beta-synthase.
 
 0.823
metH_2
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.818
FLB_05190
Glucosaminate ammonia-lyase.
   
 
 0.780
Your Current Organism:
Flavobacterium succinicans
NCBI taxonomy Id: 29536
Other names: CIP 104744, Cytophaga succinicans, DSM 4002, F. succinicans, Flavobacterium sp. DD5b, Flexibacter succinicans, IFO 14905, JCM 21151, LMG 10402, LMG:10402, NBRC 14905, NCIMB 2277, strain 8
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