STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmkThymidylate kinase. (792 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III subunit tau.
  
 
 0.802
cotSA
Spore coat protein SA.
       0.790
kanE_1
alpha-D-kanosaminyltransferase.
       0.773
FLB_17050
Putative acetyltransferase.
       0.773
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
    0.734
coaX
Type III pantothenate kinase.
   
   0.704
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.629
dgk
Deoxyguanosine kinase.
  
 
 0.624
nrdA
Ribonucleoside-diphosphate reductase 1 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.622
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.619
Your Current Organism:
Flavobacterium succinicans
NCBI taxonomy Id: 29536
Other names: CIP 104744, Cytophaga succinicans, DSM 4002, F. succinicans, Flavobacterium sp. DD5b, Flexibacter succinicans, IFO 14905, JCM 21151, LMG 10402, LMG:10402, NBRC 14905, NCIMB 2277, strain 8
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