| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FLB_19300 | pdxA | FLB_19300 | FLB_19310 | Hypothetical protein. | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. | 0.632 |
| FLB_19300 | ribBA | FLB_19300 | FLB_11980 | Hypothetical protein. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.541 |
| FLB_19300 | ribE | FLB_19300 | FLB_19320 | Hypothetical protein. | Riboflavin synthase. | 0.481 |
| FLB_19300 | rpmE2 | FLB_19300 | FLB_06120 | Hypothetical protein. | 50S ribosomal protein L31 type B; Belongs to the bacterial ribosomal protein bL31 family. | 0.468 |
| FLB_19300 | rpmF | FLB_19300 | FLB_19290 | Hypothetical protein. | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.976 |
| pdxA | FLB_19300 | FLB_19310 | FLB_19300 | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. | Hypothetical protein. | 0.632 |
| pdxA | ribBA | FLB_19310 | FLB_11980 | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.445 |
| pdxA | ribE | FLB_19310 | FLB_19320 | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. | Riboflavin synthase. | 0.651 |
| pdxA | rpmF | FLB_19310 | FLB_19290 | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.632 |
| ribBA | FLB_19300 | FLB_11980 | FLB_19300 | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Hypothetical protein. | 0.541 |
| ribBA | pdxA | FLB_11980 | FLB_19310 | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. | 0.445 |
| ribBA | ribD | FLB_11980 | FLB_06840 | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| ribBA | ribE | FLB_11980 | FLB_19320 | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Riboflavin synthase. | 0.999 |
| ribBA | ribF | FLB_11980 | FLB_14980 | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.816 |
| ribBA | ribH | FLB_11980 | FLB_04810 | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| ribBA | rpmE2 | FLB_11980 | FLB_06120 | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 50S ribosomal protein L31 type B; Belongs to the bacterial ribosomal protein bL31 family. | 0.486 |
| ribD | ribBA | FLB_06840 | FLB_11980 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
| ribD | ribE | FLB_06840 | FLB_19320 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase. | 0.999 |
| ribD | ribF | FLB_06840 | FLB_14980 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. | 0.650 |
| ribD | ribH | FLB_06840 | FLB_04810 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.997 |