STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH12106.1DNA-binding transcriptional regulator, MerR family. (289 aa)    
Predicted Functional Partners:
SEH11629.1
Diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.869
SEH12569.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.836
SEH12113.1
DICT domain-containing protein.
 
    
0.641
SEH12118.1
Ligand-binding SRPBCC domain-containing protein.
       0.600
SEH10952.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
   
 0.585
SEH13869.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
   
 0.585
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
   0.559
dnaJ-2
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
   0.559
SEH12109.1
RNA polymerase sigma-70 factor, ECF subfamily.
       0.546
SEH11373.1
DNA-binding transcriptional regulator, MerR family.
  
     0.544
Your Current Organism:
Thermoleophilum album
NCBI taxonomy Id: 29539
Other names: ATCC 35263, T. album, Thermoleiphilum album, strain HS-5
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.