node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEH13994.1 | SEH14439.1 | SAMN02745716_1444 | SAMN02745716_1633 | Anthranilate synthase component 2. | LL-diaminopimelate aminotransferase apoenzyme. | 0.551 |
SEH13994.1 | SEH14906.1 | SAMN02745716_1444 | SAMN02745716_1777 | Anthranilate synthase component 2. | Isochorismate synthase. | 0.951 |
SEH13994.1 | aroC | SAMN02745716_1444 | SAMN02745716_1525 | Anthranilate synthase component 2. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.829 |
SEH13994.1 | aroE | SAMN02745716_1444 | SAMN02745716_1511 | Anthranilate synthase component 2. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.716 |
SEH13994.1 | trpD | SAMN02745716_1444 | SAMN02745716_1445 | Anthranilate synthase component 2. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SEH13994.1 | trpE | SAMN02745716_1444 | SAMN02745716_1443 | Anthranilate synthase component 2. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
SEH14439.1 | SEH13994.1 | SAMN02745716_1633 | SAMN02745716_1444 | LL-diaminopimelate aminotransferase apoenzyme. | Anthranilate synthase component 2. | 0.551 |
SEH14439.1 | SEH14906.1 | SAMN02745716_1633 | SAMN02745716_1777 | LL-diaminopimelate aminotransferase apoenzyme. | Isochorismate synthase. | 0.777 |
SEH14439.1 | aroC | SAMN02745716_1633 | SAMN02745716_1525 | LL-diaminopimelate aminotransferase apoenzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.570 |
SEH14439.1 | aroE | SAMN02745716_1633 | SAMN02745716_1511 | LL-diaminopimelate aminotransferase apoenzyme. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.537 |
SEH14439.1 | trpE | SAMN02745716_1633 | SAMN02745716_1443 | LL-diaminopimelate aminotransferase apoenzyme. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.576 |
SEH14906.1 | SEH13994.1 | SAMN02745716_1777 | SAMN02745716_1444 | Isochorismate synthase. | Anthranilate synthase component 2. | 0.951 |
SEH14906.1 | SEH14439.1 | SAMN02745716_1777 | SAMN02745716_1633 | Isochorismate synthase. | LL-diaminopimelate aminotransferase apoenzyme. | 0.777 |
SEH14906.1 | SEH14909.1 | SAMN02745716_1777 | SAMN02745716_1778 | Isochorismate synthase. | Acetolactate synthase, small subunit. | 0.775 |
SEH14906.1 | aroC | SAMN02745716_1777 | SAMN02745716_1525 | Isochorismate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.859 |
SEH14906.1 | aroE | SAMN02745716_1777 | SAMN02745716_1511 | Isochorismate synthase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.826 |
SEH14906.1 | aroQ | SAMN02745716_1777 | SAMN02745716_1527 | Isochorismate synthase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.792 |
SEH14906.1 | menB | SAMN02745716_1777 | SAMN02745716_1773 | Isochorismate synthase. | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. | 0.824 |
SEH14906.1 | menD | SAMN02745716_1777 | SAMN02745716_1776 | Isochorismate synthase. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.976 |
SEH14906.1 | trpD | SAMN02745716_1777 | SAMN02745716_1445 | Isochorismate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.779 |