STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH15477.1Type I restriction enzyme M protein. (513 aa)    
Predicted Functional Partners:
SEH15475.1
Type I restriction enzyme, S subunit.
 
 0.997
SEH15471.1
Type I restriction enzyme, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 0.989
SEH13669.1
Type I restriction enzyme, S subunit.
 
 0.973
SEH15467.1
Hypothetical protein.
 
     0.894
SEH13664.1
Type I restriction enzyme, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 0.864
SEH10517.1
Protein of unknown function DUF45.
 
     0.530
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
   0.481
SEH14712.1
Flagellar protein FlaG.
    
   0.463
SEH15480.1
Hypothetical protein; Manually curated.
       0.406
SEH15484.1
Hypothetical protein.
       0.406
Your Current Organism:
Thermoleophilum album
NCBI taxonomy Id: 29539
Other names: ATCC 35263, T. album, Thermoleiphilum album, strain HS-5
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