STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH15591.1Drug resistance transporter, EmrB/QacA subfamily; Belongs to the major facilitator superfamily. (525 aa)    
Predicted Functional Partners:
SEH11751.1
Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
   
  0.826
SEH15589.1
DNA-binding transcriptional regulator, MarR family.
     
 0.826
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
  0.780
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
 0.776
dut
dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
     
 0.772
SEH10491.1
Ribonucleoside-diphosphate reductase beta chain.
   
 
  0.764
SEH11632.1
P-aminobenzoate N-oxygenase AurF.
   
 
  0.764
SEH12017.1
Ribonucleoside-diphosphate reductase beta chain.
   
 
  0.764
SEH15595.1
Hypothetical protein.
       0.710
SEH15431.1
MFS transporter, NNP family, nitrate/nitrite transporter.
   
 
 0.693
Your Current Organism:
Thermoleophilum album
NCBI taxonomy Id: 29539
Other names: ATCC 35263, T. album, Thermoleiphilum album, strain HS-5
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