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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C481_02502Amidohydrolase; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase. (447 aa)    
Predicted Functional Partners:
C481_02507
COG1171 Threonine dehydratase.
  
    0.784
dapD
COG2171 Tetrahydrodipicolinate N-succinyltransferase.
 
  
 0.583
C481_01245
COG3938 Proline racemase.
    
 0.555
C481_02497
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.552
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
    
  0.481
gshA
Carboxylate-amine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
    
  0.467
C481_10057
COG0405 Gamma-glutamyltransferase.
 
  
  0.464
C481_07206
Gamma-glutamyltranspeptidase; COG0405 Gamma-glutamyltransferase.
 
  
  0.445
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
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