| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C481_03082 | C481_04211 | C481_03082 | C481_04211 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; COG0717 Deoxycytidine deaminase. | 0.742 |
| C481_03082 | C481_05048 | C481_03082 | C481_05048 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; COG0127 Xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family. | 0.732 |
| C481_03082 | C481_06142 | C481_03082 | C481_06142 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. | 0.734 |
| C481_03082 | C481_10012 | C481_03082 | C481_10012 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.811 |
| C481_03082 | adk | C481_03082 | C481_09497 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.770 |
| C481_03082 | guaAA | C481_03082 | C481_14284 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | GMP synthase subunit A; Catalyzes the synthesis of GMP from XMP. | 0.763 |
| C481_03082 | guaAB | C481_03082 | C481_15585 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | GMP synthase subunit B; Catalyzes the synthesis of GMP from XMP. | 0.757 |
| C481_03082 | purA | C481_03082 | C481_12324 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.727 |
| C481_03082 | rbcL | C481_03082 | C481_09088 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. | 0.803 |
| C481_03082 | tmk | C481_03082 | C481_15195 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | COG0125 Thymidylate kinase. | 0.723 |
| C481_04211 | C481_03082 | C481_04211 | C481_03082 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; COG0717 Deoxycytidine deaminase. | COG0647 Predicted sugar phosphatases of the HAD superfamily. | 0.742 |
| C481_04211 | C481_05048 | C481_04211 | C481_05048 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; COG0717 Deoxycytidine deaminase. | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; COG0127 Xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family. | 0.899 |
| C481_04211 | C481_10012 | C481_04211 | C481_10012 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; COG0717 Deoxycytidine deaminase. | Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.567 |
| C481_04211 | tmk | C481_04211 | C481_15195 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; COG0717 Deoxycytidine deaminase. | COG0125 Thymidylate kinase. | 0.941 |
| C481_05048 | C481_03082 | C481_05048 | C481_03082 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; COG0127 Xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family. | COG0647 Predicted sugar phosphatases of the HAD superfamily. | 0.732 |
| C481_05048 | C481_04211 | C481_05048 | C481_04211 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; COG0127 Xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; COG0717 Deoxycytidine deaminase. | 0.899 |
| C481_05048 | adk | C481_05048 | C481_09497 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; COG0127 Xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.598 |
| C481_05048 | guaAA | C481_05048 | C481_14284 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; COG0127 Xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family. | GMP synthase subunit A; Catalyzes the synthesis of GMP from XMP. | 0.925 |
| C481_05048 | guaAB | C481_05048 | C481_15585 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; COG0127 Xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family. | GMP synthase subunit B; Catalyzes the synthesis of GMP from XMP. | 0.946 |
| C481_05048 | purA | C481_05048 | C481_12324 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; COG0127 Xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.948 |