Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C481_04366Pyruvoyl-dependent arginine decarboxylase. (159 aa)    
Predicted Functional Partners:
C481_05360
Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
    
 0.914
C481_05455
COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
    
 0.901
C481_04371
Hypothetical protein; COG4909 Propanediol dehydratase, large subunit.
       0.889
argH
COG0165 Argininosuccinate lyase.
     
  0.886
C481_02537
Formiminoglutamase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
    
 0.881
C481_19170
Arginase/agmatinase/formiminoglutamase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
    
 0.881
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
       0.822
C481_14678
COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.
  
   
 0.685
ala
Ornithine cyclodeaminase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
      
 0.667
C481_15895
COG1257 Hydroxymethylglutaryl-CoA reductase.
      
 0.561
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
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