| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C481_04021 | C481_04466 | C481_04021 | C481_04466 | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | 0.677 |
| C481_04021 | C481_04471 | C481_04021 | C481_04471 | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | COG2237 Predicted membrane protein. | 0.510 |
| C481_04021 | C481_15110 | C481_04021 | C481_15110 | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | COG2237 Predicted membrane protein. | 0.500 |
| C481_04021 | C481_15355 | C481_04021 | C481_15355 | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | tRNA-guanine transglycosylase; COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain. | 0.677 |
| C481_04021 | C481_17422 | C481_04021 | C481_17422 | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | Zinc finger protein; COG1326 Uncharacterized archaeal Zn-finger protein. | 0.480 |
| C481_04021 | C481_17900 | C481_04021 | C481_17900 | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | NMD3 family protein; COG1499 NMD protein affecting ribosome stability and mRNA decay. | 0.430 |
| C481_04021 | atpF | C481_04021 | C481_04411 | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.616 |
| C481_04466 | C481_04021 | C481_04466 | C481_04021 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.677 |
| C481_04466 | C481_04471 | C481_04466 | C481_04471 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | COG2237 Predicted membrane protein. | 0.924 |
| C481_04466 | C481_09128 | C481_04466 | C481_09128 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | COG1709 Predicted transcriptional regulator. | 0.700 |
| C481_04466 | C481_15110 | C481_04466 | C481_15110 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | COG2237 Predicted membrane protein. | 0.692 |
| C481_04466 | C481_15355 | C481_04466 | C481_15355 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | tRNA-guanine transglycosylase; COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain. | 0.651 |
| C481_04466 | C481_16437 | C481_04466 | C481_16437 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | Radical SAM protein; COG1031 Uncharacterized Fe-S oxidoreductase. | 0.611 |
| C481_04466 | C481_17422 | C481_04466 | C481_17422 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | Zinc finger protein; COG1326 Uncharacterized archaeal Zn-finger protein. | 0.635 |
| C481_04466 | C481_17900 | C481_04466 | C481_17900 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | NMD3 family protein; COG1499 NMD protein affecting ribosome stability and mRNA decay. | 0.632 |
| C481_04466 | atpF | C481_04466 | C481_04411 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.611 |
| C481_04466 | carS | C481_04466 | C481_06207 | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.615 |
| C481_04471 | C481_04021 | C481_04471 | C481_04021 | COG2237 Predicted membrane protein. | Peptidase M50; COG0750 Predicted membrane-associated Zn-dependent proteases 1. | 0.510 |
| C481_04471 | C481_04466 | C481_04471 | C481_04466 | COG2237 Predicted membrane protein. | Radical SAM protein; COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme. | 0.924 |
| C481_04471 | C481_09128 | C481_04471 | C481_09128 | COG2237 Predicted membrane protein. | COG1709 Predicted transcriptional regulator. | 0.728 |