Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C481_05018COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases. (332 aa)    
Predicted Functional Partners:
C481_05023
COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
       0.789
cofD
LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.709
cofE
F420-0--gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
 
   
 0.698
C481_05013
tRNA-binding domain-containing protein; COG0073 EMAP domain.
    
  0.616
C481_05028
AIR synthase-like protein domain-containing protein; COG0309 Hydrogenase maturation factor.
       0.515
C481_18745
NADPH-dependent FMN reductase; COG0431 Predicted flavoprotein.
 
 0.508
C481_02362
COG1035 Coenzyme F420-reducing hydrogenase, beta subunit.
  
  
  0.487
cofG
FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
 
   
 0.466
C481_00395
Binding-protein-dependent transporters inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.
 
 
 0.453
C481_02777
Binding-protein-dependent transporters inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; overlaps another CDS with the same product name.
 
 
 0.443
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
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