| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C481_03082 | C481_08071 | C481_03082 | C481_08071 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.801 |
| C481_03082 | C481_14388 | C481_03082 | C481_14388 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | Phospholipase-like protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. | 0.750 |
| C481_03082 | carS | C481_03082 | C481_06207 | COG0647 Predicted sugar phosphatases of the HAD superfamily. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.741 |
| C481_04086 | C481_08526 | C481_04086 | C481_08526 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.625 |
| C481_04086 | C481_13974 | C481_04086 | C481_13974 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | 0.641 |
| C481_04086 | carS | C481_04086 | C481_06207 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.785 |
| C481_04086 | ubiA-2 | C481_04086 | C481_09058 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Prenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases. | 0.766 |
| C481_04086 | ubiA-3 | C481_04086 | C481_12459 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.847 |
| C481_08071 | C481_03082 | C481_08071 | C481_03082 | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | COG0647 Predicted sugar phosphatases of the HAD superfamily. | 0.801 |
| C481_08071 | C481_14388 | C481_08071 | C481_14388 | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phospholipase-like protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. | 0.886 |
| C481_08071 | C481_14398 | C481_08071 | C481_14398 | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-alcohol phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.845 |
| C481_08071 | carS | C481_08071 | C481_06207 | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.873 |
| C481_08526 | C481_04086 | C481_08526 | C481_04086 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.625 |
| C481_08526 | C481_13974 | C481_08526 | C481_13974 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | 0.729 |
| C481_08526 | carS | C481_08526 | C481_06207 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.712 |
| C481_08526 | ubiA-2 | C481_08526 | C481_09058 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Prenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases. | 0.730 |
| C481_08526 | ubiA-3 | C481_08526 | C481_12459 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.795 |
| C481_13974 | C481_04086 | C481_13974 | C481_04086 | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.641 |
| C481_13974 | C481_08526 | C481_13974 | C481_08526 | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.729 |
| C481_13974 | carS | C481_13974 | C481_06207 | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.778 |