| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C481_04086 | C481_08526 | C481_04086 | C481_08526 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.627 |
| C481_04086 | C481_13974 | C481_04086 | C481_13974 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | 0.643 |
| C481_04086 | C481_16697 | C481_04086 | C481_16697 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.639 |
| C481_04086 | carS | C481_04086 | C481_06207 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.908 |
| C481_04086 | ubiA-3 | C481_04086 | C481_12459 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.950 |
| C481_08071 | C481_14398 | C481_08071 | C481_14398 | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-alcohol phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.657 |
| C481_08071 | carS | C481_08071 | C481_06207 | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.827 |
| C481_08071 | tpiA | C481_08071 | C481_08086 | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.810 |
| C481_08526 | C481_04086 | C481_08526 | C481_04086 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.627 |
| C481_08526 | C481_13974 | C481_08526 | C481_13974 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | 0.888 |
| C481_08526 | carS | C481_08526 | C481_06207 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.901 |
| C481_08526 | tpiA | C481_08526 | C481_08086 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.400 |
| C481_08526 | ubiA-3 | C481_08526 | C481_12459 | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | Prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.929 |
| C481_13974 | C481_04086 | C481_13974 | C481_04086 | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.643 |
| C481_13974 | C481_08526 | C481_13974 | C481_08526 | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.888 |
| C481_13974 | C481_16697 | C481_13974 | C481_16697 | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | Geranylgeranyl reductase; COG0644 Dehydrogenases (flavoproteins). | 0.889 |
| C481_13974 | carS | C481_13974 | C481_06207 | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.926 |
| C481_13974 | ubiA-3 | C481_13974 | C481_12459 | FAD dependent oxidoreductase; COG0644 Dehydrogenases (flavoproteins). | Prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.948 |
| C481_14398 | C481_08071 | C481_14398 | C481_08071 | CDP-alcohol phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.657 |
| C481_14398 | carS | C481_14398 | C481_06207 | CDP-alcohol phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.912 |