STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C481_08321COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit. (290 aa)    
Predicted Functional Partners:
C481_08316
Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
 
 0.999
C481_13834
2-oxoglutarate synthase; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
 
 0.996
C481_19795
Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
  
 
 0.950
C481_15080
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.897
C481_07726
COG0281 Malic enzyme.
     
 0.866
C481_08281
COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.
    
 0.856
C481_02702
CoA-binding domain-containing protein; COG1042 Acyl-CoA synthetase (NDP forming).
    
 0.848
C481_10975
CoA-binding protein; COG1042 Acyl-CoA synthetase (NDP forming).
    
 0.848
C481_12164
COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I).
  
 0.839
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.811
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.