Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C481_08768Peptidase S1 and S6 chymotrypsin/Hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (385 aa)    
Predicted Functional Partners:
C481_15500
Peptidase S1 and S6 chymotrypsin/Hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
     
  0.886
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.876
C481_02392
Peptidase S1 and S6 chymotrypsin/Hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
     
  0.819
C481_15820
Periplasmic serine proteinase; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
     
  0.814
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
    
 0.811
pan-2
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
    
 0.811
C481_08763
G6PDH family F420-dependent oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
       0.767
C481_18045
Hypothetical protein; COG0457 FOG: TPR repeat.
   
 0.674
rpl11p
50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
 
   0.669
rps9p
COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
    
 
 0.622
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
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