Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C481_08883DNA methylase N-4/N-6 domain-containing protein; COG0863 DNA modification methylase. (370 aa)    
Predicted Functional Partners:
C481_13199
Hypothetical protein.
  
     0.684
C481_05860
Hypothetical protein.
  
     0.663
C481_13084
PAS/PAC sensor protein; COG2203 FOG: GAF domain.
  
     0.651
C481_17895
Pyrrolo-quinoline quinone; COG1520 FOG: WD40-like repeat.
  
     0.582
ubiA-2
Prenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases.
  
     0.581
C481_17407
Response regulator receiver modulated GAF sensor protein; COG0784 FOG: CheY-like receiver.
  
   
 0.564
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
    0.563
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
    0.563
C481_08873
COG1757 Na+/H+ antiporter.
       0.535
C481_08878
TRAM domain-containing protein.
       0.535
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
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