| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C481_04061 | C481_06871 | C481_04061 | C481_06871 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | 0.997 |
| C481_04061 | C481_06876 | C481_04061 | C481_06876 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | Glycine dehydrogenase subunit 1; COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain. | 0.994 |
| C481_04061 | C481_18505 | C481_04061 | C481_18505 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | Dimethylglycine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.866 |
| C481_04061 | C481_19800 | C481_04061 | C481_19800 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.939 |
| C481_04061 | folD | C481_04061 | C481_13434 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.930 |
| C481_04061 | gcvH | C481_04061 | C481_09138 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.997 |
| C481_04061 | gcvT | C481_04061 | C481_09143 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. | 0.881 |
| C481_04061 | glyA | C481_04061 | C481_11680 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.945 |
| C481_04061 | glyA-2 | C481_04061 | C481_18485 | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.945 |
| C481_06871 | C481_04061 | C481_06871 | C481_04061 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | 0.997 |
| C481_06871 | C481_06876 | C481_06871 | C481_06876 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Glycine dehydrogenase subunit 1; COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain. | 0.999 |
| C481_06871 | C481_18505 | C481_06871 | C481_18505 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Dimethylglycine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating). | 0.992 |
| C481_06871 | C481_19800 | C481_06871 | C481_19800 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.951 |
| C481_06871 | folD | C481_06871 | C481_13434 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.966 |
| C481_06871 | gcvH | C481_06871 | C481_09138 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| C481_06871 | gcvT | C481_06871 | C481_09143 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| C481_06871 | glyA | C481_06871 | C481_11680 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.961 |
| C481_06871 | glyA-2 | C481_06871 | C481_18485 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.961 |
| C481_06871 | lipA | C481_06871 | C481_19775 | Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.551 |
| C481_06876 | C481_04061 | C481_06876 | C481_04061 | Glycine dehydrogenase subunit 1; COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain. | Folate-binding protein YgfZ; COG0404 Glycine cleavage system T protein (aminomethyltransferase). | 0.994 |