Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
matS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (401 aa)    
Predicted Functional Partners:
C481_07126
COG0620 Methionine synthase II (cobalamin-independent).
  
  
  0.900
C481_16997
COG2873 O-acetylhomoserine sulfhydrylase.
     
  0.886
C481_18375
COG2873 O-acetylhomoserine sulfhydrylase.
     
  0.886
C481_11235
Adenylyl cyclase CyaB; COG1437 Adenylate cyclase, class 2 (thermophilic).
 
     0.850
metE
Methionine synthase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.
  
  
  0.846
C481_00640
COG0620 Methionine synthase II (cobalamin-independent).
     
  0.816
C481_20026
COG0620 Methionine synthase II (cobalamin-independent).
     
  0.816
C481_11230
COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2.
 
  
 0.804
thiI
Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
     0.615
C481_03412
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
     
  0.586
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
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