Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C481_12939Metallophosphoesterase; COG1407 Predicted ICC-like phosphoesterases. (299 aa)    
Predicted Functional Partners:
C481_12944
COG3390 Uncharacterized protein conserved in archaea.
 
   
 0.989
C481_12949
Replication factor A; COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins.
 
   
 0.989
C481_12039
DEAD/DEAH box helicase; COG1201 Lhr-like helicases.
 
    0.811
C481_17137
Replication factor A; COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins.
 
   
 0.772
C481_17167
Replication factor A; COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins.
 
   
 0.707
C481_17132
COG3390 Uncharacterized protein conserved in archaea.
  
   
 0.695
C481_18625
Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication.
  
     0.660
endA
tRNA splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
   
 0.652
C481_08521
Hypothetical protein; COG1938 Archaeal enzymes of ATP-grasp superfamily.
  
     0.628
C481_12959
COG1985 Pyrimidine reductase, riboflavin biosynthesis.
       0.628
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
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