Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C481_17652COG0180 Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (413 aa)    
Predicted Functional Partners:
trpS
tryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp).
     
  0.819
pheT
COG0072 Phenylalanyl-tRNA synthetase beta subunit.
 
  
 0.787
tyrS
tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
 
  
 0.786
pheS
COG0016 Phenylalanyl-tRNA synthetase alpha subunit.
 
  
 0.758
serS
seryl-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
 
 0.743
infB
Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
  
 0.694
cysS
COG0215 Cysteinyl-tRNA synthetase.
 
  
 0.672
C481_04808
Thermosome; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.
  
 
 
 0.668
C481_17632
Thermosome; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family.
  
 
 
 0.659
argS
COG0018 Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.653
Your Current Organism:
Natrialba asiatica
NCBI taxonomy Id: 29540
Other names: N. asiatica DSM 12278, Natrialba asiatica 172P1, Natrialba asiatica DSM 12278, halophilic archaebacterium 172P1, halophilic archaeon 172P1, halophilic bacteria (strain 172P1), halophilic bacteria strain 172P1, halophilic bacterium (strain 172P1)
Server load: medium (44%) [HD]