Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| exo | folD | MCAN360_0498 | MCAN360_0040 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.618 |
| exo | glyA | MCAN360_0498 | MCAN360_0118 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.817 |
| exo | gmk | MCAN360_0498 | MCAN360_0227 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.812 |
| exo | metG | MCAN360_0498 | MCAN360_0617 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]. | 0.891 |
| fmt | folD | MCAN360_0224 | MCAN360_0040 | COG0223 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]. | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.962 |
| fmt | glyA | MCAN360_0224 | MCAN360_0118 | COG0223 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| fmt | gmk | MCAN360_0224 | MCAN360_0227 | COG0223 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.529 |
| fmt | metG | MCAN360_0224 | MCAN360_0617 | COG0223 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]. | COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]. | 0.963 |
| fmt | pepB | MCAN360_0224 | MCAN360_0219 | COG0223 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]. | Aminopeptidase; COG0260 Leucyl aminopeptidase [Amino acid transport and metabolism]; leucine aminopeptidase; Belongs to the peptidase M17 family. | 0.529 |
| fmt | pepB-2 | MCAN360_0224 | MCAN360_0221 | COG0223 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]. | Aminopeptidase; COG0260 Leucyl aminopeptidase [Amino acid transport and metabolism]; leucine aminopeptidase; Belongs to the peptidase M17 family. | 0.549 |
| folD | exo | MCAN360_0040 | MCAN360_0498 | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | 0.618 |
| folD | fmt | MCAN360_0040 | MCAN360_0224 | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | COG0223 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]. | 0.962 |
| folD | glyA | MCAN360_0040 | MCAN360_0118 | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.966 |
| glyA | exo | MCAN360_0118 | MCAN360_0498 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | 0.817 |
| glyA | fmt | MCAN360_0118 | MCAN360_0224 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COG0223 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]. | 0.923 |
| glyA | folD | MCAN360_0118 | MCAN360_0040 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.966 |
| glyA | gmk | MCAN360_0118 | MCAN360_0227 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.699 |
| glyA | lpd | MCAN360_0118 | MCAN360_0609 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; COG1635 Ribulose 1,5-bisphosphate synthetase, converts PRPP to RuBP, flavoprotein [Carbohydrate transport and metabolism]. | 0.941 |
| glyA | metG | MCAN360_0118 | MCAN360_0617 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]. | 0.762 |
| glyA | pepB | MCAN360_0118 | MCAN360_0219 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminopeptidase; COG0260 Leucyl aminopeptidase [Amino acid transport and metabolism]; leucine aminopeptidase; Belongs to the peptidase M17 family. | 0.808 |
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