STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III polC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1437 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.951
dnaN
DNA polymerase III beta chain; COG0592 DNA polymerase sliding clamp subunit (PCNA homolog) [DNA replication, recombination, and repair].
   
 0.950
dnaE
COG0587 DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].
    
0.949
holA
COG1466 DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; delta subunit.
    
 0.923
BAP39661.1
PRK07132 DNA polymerase III subunit delta'.
  
 0.918
exo
COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair].
   
 
 0.862
cdsA
Phosphatidate cytidylyltransferase; COG0575 CDP-diglyceride synthetase [Lipid metabolism]; Belongs to the CDS family.
       0.772
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.728
frr
COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis].
       0.604
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.599
Your Current Organism:
Mycoplasma canadense
NCBI taxonomy Id: 29554
Other names: ATCC 29418, M. canadense, Metamycoplasma canadense, NCTC 10152, strain 275C
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