Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gpsA | plsC | MCAN360_0451 | MCAN360_0484 | COG0240 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]. | 0.865 |
| gpsA | plsY | MCAN360_0451 | MCAN360_0177 | COG0240 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.980 |
| gpsA | topA | MCAN360_0451 | MCAN360_0443 | COG0240 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.427 |
| grpE | hrcA | MCAN360_0180 | MCAN360_0178 | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.989 |
| grpE | lon | MCAN360_0180 | MCAN360_0181 | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | COG0466 ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; COG1618 predicted nucleotide kinase [Nucleotide transport and metabolism]. | 0.854 |
| grpE | plsY | MCAN360_0180 | MCAN360_0177 | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.572 |
| grpE | yidC | MCAN360_0180 | MCAN360_0245 | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | COG0201 Preprotein translocase subunit SecY [Intracellular trafficking and secretion]; COG0706 Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; predicted membrane protein, OxaA/YidC family. | 0.486 |
| hrcA | grpE | MCAN360_0178 | MCAN360_0180 | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.989 |
| hrcA | lon | MCAN360_0178 | MCAN360_0181 | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | COG0466 ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; COG1618 predicted nucleotide kinase [Nucleotide transport and metabolism]. | 0.616 |
| hrcA | plsY | MCAN360_0178 | MCAN360_0177 | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.568 |
| iap | plsY | MCAN360_0176 | MCAN360_0177 | Hypothetical protein; COG2234 predicted aminopeptidases [General function prediction only]; predicted lipoprotein. | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.469 |
| lon | grpE | MCAN360_0181 | MCAN360_0180 | COG0466 ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; COG1618 predicted nucleotide kinase [Nucleotide transport and metabolism]. | grpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.854 |
| lon | hrcA | MCAN360_0181 | MCAN360_0178 | COG0466 ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; COG1618 predicted nucleotide kinase [Nucleotide transport and metabolism]. | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.616 |
| lon | plsY | MCAN360_0181 | MCAN360_0177 | COG0466 ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; COG1618 predicted nucleotide kinase [Nucleotide transport and metabolism]. | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.462 |
| pheT | plsY | MCAN360_0062 | MCAN360_0177 | COG0072 Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; COG0073 EMAP domain [General function prediction only]; pheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.435 |
| pheT | topA | MCAN360_0062 | MCAN360_0443 | COG0072 Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; COG0073 EMAP domain [General function prediction only]; pheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.880 |
| pheT | yidC | MCAN360_0062 | MCAN360_0245 | COG0072 Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; COG0073 EMAP domain [General function prediction only]; pheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | COG0201 Preprotein translocase subunit SecY [Intracellular trafficking and secretion]; COG0706 Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; predicted membrane protein, OxaA/YidC family. | 0.462 |
| plsC | gpsA | MCAN360_0484 | MCAN360_0451 | COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]. | COG0240 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.865 |
| plsC | plsX | MCAN360_0484 | MCAN360_0122 | COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]. | Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.524 |
| plsC | plsY | MCAN360_0484 | MCAN360_0177 | COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]. | Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.940 |
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