STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cofHypothetical protein; COG0561predicted hydrolases of the HAD superfamily [General function prediction only]; putative COF family HAD hydrolase. (270 aa)    
Predicted Functional Partners:
trxA
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; COG3118 Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Belongs to the thioredoxin family.
  
    0.779
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
    0.639
cof-3
Hypothetical protein, putative COF family HAD hydrolase; COG0560 Phosphoserine phosphatase [Amino acid transport and metabolism]; COG0561 predicted hydrolases of the HAD superfamily [General function prediction only]; COG1778 Low specificity phosphatase (HAD superfamily) [General function prediction only].
  
     0.500
Your Current Organism:
Mycoplasma canadense
NCBI taxonomy Id: 29554
Other names: ATCC 29418, M. canadense, Metamycoplasma canadense, NCTC 10152, strain 275C
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