node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
frr | fusA | MCAN360_0139 | MCAN360_0633 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.995 |
frr | pyrH | MCAN360_0139 | MCAN360_0140 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.995 |
frr | rplD | MCAN360_0139 | MCAN360_0663 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.997 |
frr | rplL | MCAN360_0139 | MCAN360_0642 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.907 |
frr | rplS | MCAN360_0139 | MCAN360_0768 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.995 |
frr | rpsB | MCAN360_0139 | MCAN360_0528 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | COG0052 Ribosomal protein S2 [Translation, ribosomal structure and biogenesis]; Belongs to the universal ribosomal protein uS2 family. | 0.998 |
frr | rpsI | MCAN360_0139 | MCAN360_0739 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | COG0103 Ribosomal protein S9 [Translation, ribosomal structure and biogenesis]; Belongs to the universal ribosomal protein uS9 family. | 0.996 |
frr | tig | MCAN360_0139 | MCAN360_0404 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.853 |
frr | tsf | MCAN360_0139 | MCAN360_0529 | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.965 |
fusA | frr | MCAN360_0633 | MCAN360_0139 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | 0.995 |
fusA | rplD | MCAN360_0633 | MCAN360_0663 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.999 |
fusA | rplL | MCAN360_0633 | MCAN360_0642 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.999 |
fusA | rplS | MCAN360_0633 | MCAN360_0768 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.999 |
fusA | rpsB | MCAN360_0633 | MCAN360_0528 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | COG0052 Ribosomal protein S2 [Translation, ribosomal structure and biogenesis]; Belongs to the universal ribosomal protein uS2 family. | 0.999 |
fusA | rpsI | MCAN360_0633 | MCAN360_0739 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | COG0103 Ribosomal protein S9 [Translation, ribosomal structure and biogenesis]; Belongs to the universal ribosomal protein uS9 family. | 0.998 |
fusA | tig | MCAN360_0633 | MCAN360_0404 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.814 |
fusA | tsf | MCAN360_0633 | MCAN360_0529 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.963 |
fusA | tufB | MCAN360_0633 | MCAN360_0606 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.998 |
pyrH | frr | MCAN360_0140 | MCAN360_0139 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | COG0233 Ribosome recycling factor [Translation, ribosomal structure and biogenesis]. | 0.995 |
pyrH | rpsB | MCAN360_0140 | MCAN360_0528 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | COG0052 Ribosomal protein S2 [Translation, ribosomal structure and biogenesis]; Belongs to the universal ribosomal protein uS2 family. | 0.975 |