Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaJ | exo | MCAN360_0440 | MCAN360_0498 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | 0.573 |
| dnaJ | metG | MCAN360_0440 | MCAN360_0617 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]. | 0.531 |
| dnaJ | metK | MCAN360_0440 | MCAN360_0600 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.560 |
| dnaJ | msrA | MCAN360_0440 | MCAN360_0596 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.606 |
| dnaJ | pheT | MCAN360_0440 | MCAN360_0062 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | COG0072 Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; COG0073 EMAP domain [General function prediction only]; pheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.503 |
| dnaJ | potB | MCAN360_0440 | MCAN360_0158 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | COG1176 ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism]; COG1177 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]. | 0.511 |
| exo | dnaJ | MCAN360_0498 | MCAN360_0440 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.573 |
| exo | glyA | MCAN360_0498 | MCAN360_0118 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.817 |
| exo | metG | MCAN360_0498 | MCAN360_0617 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]. | 0.891 |
| exo | metK | MCAN360_0498 | MCAN360_0600 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.797 |
| exo | mscL | MCAN360_0498 | MCAN360_0270 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | COG1970 Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]. | 0.535 |
| exo | msrA | MCAN360_0498 | MCAN360_0596 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.986 |
| exo | pgk | MCAN360_0498 | MCAN360_0602 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | COG0126 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Belongs to the phosphoglycerate kinase family. | 0.654 |
| exo | pheT | MCAN360_0498 | MCAN360_0062 | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | COG0072 Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; COG0073 EMAP domain [General function prediction only]; pheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.885 |
| glyA | exo | MCAN360_0118 | MCAN360_0498 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. | 0.817 |
| glyA | metG | MCAN360_0118 | MCAN360_0617 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]. | 0.762 |
| glyA | metK | MCAN360_0118 | MCAN360_0600 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.596 |
| glyA | pgk | MCAN360_0118 | MCAN360_0602 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COG0126 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Belongs to the phosphoglycerate kinase family. | 0.479 |
| glyA | pheT | MCAN360_0118 | MCAN360_0062 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COG0072 Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; COG0073 EMAP domain [General function prediction only]; pheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.586 |
| metG | dnaJ | MCAN360_0617 | MCAN360_0440 | COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.531 |
page 1 of 3