STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (890 aa)    
Predicted Functional Partners:
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
   
 0.999
glnS
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.997
metG
COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].
  
0.989
argS
COG0018 Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].
  
 0.988
leuS
COG0495 Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
0.987
pheT
COG0072 Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; COG0073 EMAP domain [General function prediction only]; pheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.985
asnS
asparaginyl-tRNA-synthetase; COG0017 Aspartyl/asparaginyl-tRNA synthetases [Translation, ribosomal structure and biogenesis].
  
 0.944
lysU
COG1190 Lysyl-tRNA synthetase (class II) [Translation, ribosomal structure and biogenesis]; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.904
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
  
  
 0.863
valS
Fusion of oligopeptide transport protein OppF and Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
  
 
0.858
Your Current Organism:
Mycoplasma canadense
NCBI taxonomy Id: 29554
Other names: ATCC 29418, M. canadense, Metamycoplasma canadense, NCTC 10152, strain 275C
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