STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (284 aa)    
Predicted Functional Partners:
MCYN0549
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.959
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
 
 0.945
AKF41504.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.936
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.927
stp
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.835
nusB
Antitermination protein NusB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.833
AKF40937.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.821
AKF40938.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.808
hisS
histidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.806
AKF40935.1
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.769
Your Current Organism:
Mycoplasma canis
NCBI taxonomy Id: 29555
Other names: ATCC 19525, Asterococcus canis, IFO 14846, M. canis, Mycoplasmopsis canis, NBRC 14846, NCTC 10146, strain PG 14, strain PG14, strain beta
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