cls protein (Mycoplasma gallinaceum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

cls

Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)

Predicted Functional Partners:

nifU

0.809

rpiB

0.783

AKA49744.1

0.670

ptsH

0.615

pdhC_2

0.523

plsC

0.523

hsdR

0.479

MCYN0206

0.467

gsiD_1

0.466

MCYN0748

0.416

Your Current Organism:

Mycoplasma gallinaceum

NCBI taxonomy Id: 29556
Other names: ATCC 33550, M. gallinaceum, NCTC 10183, strain DD

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKA49744.1	cls	VO56_00395	VO56_00180	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.670
MCYN0206	cls	VO56_02595	VO56_00180	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.467
MCYN0748	cls	VO56_01840	VO56_00180	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
MCYN0748	nifU	VO56_01840	VO56_00650	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.453
MCYN0748	pdhC_2	VO56_01840	VO56_01030	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.568
cls	AKA49744.1	VO56_00180	VO56_00395	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.670
cls	MCYN0206	VO56_00180	VO56_02595	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.467
cls	MCYN0748	VO56_00180	VO56_01840	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.416
cls	gsiD_1	VO56_00180	VO56_00195	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.466
cls	hsdR	VO56_00180	VO56_00170	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.	0.479
cls	nifU	VO56_00180	VO56_00650	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.809
cls	pdhC_2	VO56_00180	VO56_01030	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.523
cls	plsC	VO56_00180	VO56_02295	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.523
cls	ptsH	VO56_00180	VO56_00185	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.615
cls	rpiB	VO56_00180	VO56_00175	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.783
gsiD_1	cls	VO56_00195	VO56_00180	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.466
gsiD_1	ptsH	VO56_00195	VO56_00185	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.619
hsdR	cls	VO56_00170	VO56_00180	Hypothetical protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.	Cardiolipin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.479
hsdR	rpiB	VO56_00170	VO56_00175	Hypothetical protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.	Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.449
nifU	MCYN0748	VO56_00650	VO56_01840	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]	0.453