STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDE43020.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (193 aa)    
Predicted Functional Partners:
atpE
ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
  0.999
KDE43021.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     0.994
KDE42539.1
Metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.993
KDE43003.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.917
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
 0.858
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.807
KDE43019.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.787
KDE43022.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.787
KDE43004.1
DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.785
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
  0.769
Your Current Organism:
Mycoplasma hyosynoviae
NCBI taxonomy Id: 29559
Other names: ATCC 25591, M. hyosynoviae, Metamycoplasma hyosynoviae, Mycoplasma suidaniae, NCTC 10167, strain S-16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.