node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHM03098.1 | SHM12176.1 | SAMN05878437_0873 | SAMN05878437_1325 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | SAM-dependent methyltransferase. | 0.418 |
SHM03098.1 | rlmL | SAMN05878437_0873 | SAMN05878437_2731 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.555 |
SHM12149.1 | SHM12176.1 | SAMN05878437_1324 | SAMN05878437_1325 | L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. | SAM-dependent methyltransferase. | 0.746 |
SHM12149.1 | mutM | SAMN05878437_1324 | SAMN05878437_1326 | L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.703 |
SHM12149.1 | rpmG | SAMN05878437_1324 | SAMN05878437_1327 | L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. | LSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family. | 0.483 |
SHM12176.1 | SHM03098.1 | SAMN05878437_1325 | SAMN05878437_0873 | SAM-dependent methyltransferase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.418 |
SHM12176.1 | SHM12149.1 | SAMN05878437_1325 | SAMN05878437_1324 | SAM-dependent methyltransferase. | L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. | 0.746 |
SHM12176.1 | dut | SAMN05878437_1325 | SAMN05878437_1331 | SAM-dependent methyltransferase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.468 |
SHM12176.1 | mutM | SAMN05878437_1325 | SAMN05878437_1326 | SAM-dependent methyltransferase. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.802 |
SHM12176.1 | rlmL | SAMN05878437_1325 | SAMN05878437_2731 | SAM-dependent methyltransferase. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.436 |
SHM12176.1 | rpmB | SAMN05878437_1325 | SAMN05878437_1328 | SAM-dependent methyltransferase. | LSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family. | 0.649 |
SHM12176.1 | rpmG | SAMN05878437_1325 | SAMN05878437_1327 | SAM-dependent methyltransferase. | LSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family. | 0.689 |
dut | SHM12176.1 | SAMN05878437_1331 | SAMN05878437_1325 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | SAM-dependent methyltransferase. | 0.468 |
dut | rlmL | SAMN05878437_1331 | SAMN05878437_2731 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.419 |
mutM | SHM12149.1 | SAMN05878437_1326 | SAMN05878437_1324 | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. | 0.703 |
mutM | SHM12176.1 | SAMN05878437_1326 | SAMN05878437_1325 | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | SAM-dependent methyltransferase. | 0.802 |
mutM | rpmB | SAMN05878437_1326 | SAMN05878437_1328 | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | LSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family. | 0.486 |
mutM | rpmG | SAMN05878437_1326 | SAMN05878437_1327 | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | LSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family. | 0.587 |
rlmL | SHM03098.1 | SAMN05878437_2731 | SAMN05878437_0873 | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.555 |
rlmL | SHM12176.1 | SAMN05878437_2731 | SAMN05878437_1325 | 23S rRNA m(2)G-2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | SAM-dependent methyltransferase. | 0.436 |