STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM12519.1Transcriptional regulator, BolA protein family; Belongs to the BolA/IbaG family. (102 aa)    
Predicted Functional Partners:
SHM42620.1
Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.981
SHM12476.1
Ribosomal-protein-alanine N-acetyltransferase.
       0.873
SHM12497.1
Hypothetical protein.
       0.873
SHM12533.1
MFS transporter, DHA2 family, multidrug resistance protein.
       0.763
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
 
 
 
 0.674
SHM31311.1
Starvation-inducible DNA-binding protein; Belongs to the Dps family.
   
    0.577
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
    
  0.528
SHM12549.1
Hypothetical protein.
       0.470
SHM43331.1
Hypothetical protein.
  
     0.419
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
      
 0.418
Your Current Organism:
Halomonas subglaciescola
NCBI taxonomy Id: 29571
Other names: ACAM 12, ATCC 43668, CIP 104042, DSM 4683, H. subglaciescola, IFO 14766, JCM 21045, LMG 8824, LMG:8824, NBRC 14766, UQM 2926
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