STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (295 aa)    
Predicted Functional Partners:
ARQ73836.1
2-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
 
 
 0.969
prpD
2-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.940
acnD
Fe/S-dependent 2-methylisocitrate dehydratase AcnD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.870
ARQ73834.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.850
gltA
Type II citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
 
 
 0.813
prpF
2-methylaconitate cis-trans isomerase PrpF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.757
ARQ74496.1
2-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.704
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
  
 0.695
acnB
Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family.
    
 0.619
ARQ75597.1
4-oxalomesaconate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.509
Your Current Organism:
Pseudomonas fragi
NCBI taxonomy Id: 296
Other names: ATCC 4973, Bacterium fragi, CCUG 556, CFBP 4556, CIP 55.4, DSM 3456, HAMBI 28, IFO 3458, LMG 2191, LMG:2191, NBRC 3458, NCCB 69033, NCIB 8542, NCIB:8542, NCTC 10689, NRRL B-25, NRRL B-727, NRRL:B:25, P. fragi, Pseudomonas fragariae, VKM B-898, VKM:B:898
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