STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARQ76954.1Nickel-responsive transcriptional regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (135 aa)    
Predicted Functional Partners:
nikA
Nickel ABC transporter, nickel/metallophore periplasmic binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.657
nikD
Nickel import ATP-binding protein NikD; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
     
 0.651
ARQ74575.1
Nickel ABC transporter permease subunit NikC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.617
ARQ74576.1
Nickel ABC transporter permease subunit NikB; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.610
nikE
Nickel import ATP-binding protein NikE; With NikABCD is involved with nickel transport into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
rrf
5S ribosomal RNA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.476
ARQ73057.1
Molybdenum-dependent transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.420
Your Current Organism:
Pseudomonas fragi
NCBI taxonomy Id: 296
Other names: ATCC 4973, Bacterium fragi, CCUG 556, CFBP 4556, CIP 55.4, DSM 3456, HAMBI 28, IFO 3458, LMG 2191, LMG:2191, NBRC 3458, NCCB 69033, NCIB 8542, NCIB:8542, NCTC 10689, NRRL B-25, NRRL B-727, NRRL:B:25, P. fragi, Pseudomonas fragariae, VKM B-898, VKM:B:898
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