STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZOSMA_97G00590SP-RING-type domain-containing protein. (875 aa)    
Predicted Functional Partners:
ZOSMA_42G00610
Small ubiquitin-related modifier.
    
 0.983
ZOSMA_26G00070
Ubiquitin-conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.970
A0A0K9PTY7
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.848
ZOSMA_52G00120
E3 SUMO-protein ligase MMS21.
    
 
 0.828
ZOSMA_8G01920
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.821
ZOSMA_26G00450
ATP-dependent DNA helicase 2 subunit KU70.
    
 0.713
A0A0K9PR77
Cullin 4; Belongs to the cullin family.
     
 0.691
A0A0K9PYR3
Histone-lysine N-methyltransferase.
   
 0.670
ZOSMA_89G00330
DNA cross-link repair 1B protein.
   
 0.668
ZOSMA_59G00350
DNA cross-link repair 1A protein.
   
 0.668
Your Current Organism:
Zostera marina
NCBI taxonomy Id: 29655
Other names: Z. marina, Zostera marina L.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.