A0A0K9NM10 protein (Zostera marina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A0K9NM10

30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family. (81 aa)

Predicted Functional Partners:

ZOSMA_13G00550

0.998

ZOSMA_22G00510

0.996

ZOSMA_41G00510

0.995

rps7

0.993

ZOSMA_2G00760

0.993

ZOSMA_53G00490

0.992

A0A0K9NXU6

0.992

ZOSMA_34G01030

0.992

ZOSMA_22G01040

0.992

ZOSMA_1G02040

0.992

Your Current Organism:

Zostera marina

NCBI taxonomy Id: 29655
Other names: Z. marina, Zostera marina L.

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0K9NM10	A0A0K9NXU6	A0A0K9NM10	A0A0K9NXU6	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	30S ribosomal protein S14, chloroplastic.	0.992
A0A0K9NM10	ZOSMA_13G00550	A0A0K9NM10	A0A0K9PXW1	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	Ribosomal protein S6 family protein.	0.998
A0A0K9NM10	ZOSMA_1G02040	A0A0K9NM10	A0A0K9PMQ2	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	Ribosomal protein S14, mitochondrial.	0.992
A0A0K9NM10	ZOSMA_22G00510	A0A0K9NM10	A0A0K9PKK5	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	Trigger_N domain-containing protein.	0.996
A0A0K9NM10	ZOSMA_22G01040	A0A0K9NM10	A0A0K9PIM3	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	50S ribosomal protein L33.	0.992
A0A0K9NM10	ZOSMA_2G00760	A0A0K9NM10	A0A0K9PAS0	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.993
A0A0K9NM10	ZOSMA_34G01030	A0A0K9NM10	A0A0K9P735	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	Ribosomal protein 5B; Belongs to the universal ribosomal protein uS7 family.	0.992
A0A0K9NM10	ZOSMA_41G00510	A0A0K9NM10	A0A0K9P4R1	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family.	0.995
A0A0K9NM10	ZOSMA_53G00490	A0A0K9NM10	A0A0K9NWY4	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	30S ribosomal protein S18 family; Belongs to the bacterial ribosomal protein bS18 family.	0.992
A0A0K9NM10	rps7	A0A0K9NM10	A0A0K9NWD0	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	Ribosomal protein S7, mitochondrial.	0.993
A0A0K9NXU6	A0A0K9NM10	A0A0K9NXU6	A0A0K9NM10	30S ribosomal protein S14, chloroplastic.	30S ribosomal protein S12, chloroplastic; Belongs to the universal ribosomal protein uS12 family.	0.992
A0A0K9NXU6	ZOSMA_13G00550	A0A0K9NXU6	A0A0K9PXW1	30S ribosomal protein S14, chloroplastic.	Ribosomal protein S6 family protein.	0.998
A0A0K9NXU6	ZOSMA_1G02040	A0A0K9NXU6	A0A0K9PMQ2	30S ribosomal protein S14, chloroplastic.	Ribosomal protein S14, mitochondrial.	0.851
A0A0K9NXU6	ZOSMA_22G00510	A0A0K9NXU6	A0A0K9PKK5	30S ribosomal protein S14, chloroplastic.	Trigger_N domain-containing protein.	0.997
A0A0K9NXU6	ZOSMA_22G01040	A0A0K9NXU6	A0A0K9PIM3	30S ribosomal protein S14, chloroplastic.	50S ribosomal protein L33.	0.995
A0A0K9NXU6	ZOSMA_2G00760	A0A0K9NXU6	A0A0K9PAS0	30S ribosomal protein S14, chloroplastic.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.996
A0A0K9NXU6	ZOSMA_34G01030	A0A0K9NXU6	A0A0K9P735	30S ribosomal protein S14, chloroplastic.	Ribosomal protein 5B; Belongs to the universal ribosomal protein uS7 family.	0.994
A0A0K9NXU6	ZOSMA_41G00510	A0A0K9NXU6	A0A0K9P4R1	30S ribosomal protein S14, chloroplastic.	Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family.	0.996
A0A0K9NXU6	ZOSMA_53G00490	A0A0K9NXU6	A0A0K9NWY4	30S ribosomal protein S14, chloroplastic.	30S ribosomal protein S18 family; Belongs to the bacterial ribosomal protein bS18 family.	0.995
A0A0K9NXU6	rps7	A0A0K9NXU6	A0A0K9NWD0	30S ribosomal protein S14, chloroplastic.	Ribosomal protein S7, mitochondrial.	0.995

page 1 of 5

Network Stats

number of nodes:

9

number of edges:

23

average node degree:

5.11

avg. local clustering coefficient:

0.948

expected number of edges:

13

PPI enrichment p-value:

0.00676

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006366

Transcription by RNA polymerase II

10 of 96

2.47

9.23

5.24e-21

GO:0006367

Transcription initiation from RNA polymerase II promoter

5 of 30

2.67

5.11

1.64e-10

GO:0006360

Transcription by RNA polymerase I

4 of 22

2.71

4.11

1.89e-08

GO:0006383

Transcription by RNA polymerase III

4 of 26

2.64

3.96

3.18e-08

GO:0042797

tRNA transcription by RNA polymerase III

2 of 2

3.45

2.26

8.67e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

4 of 32

2.55

3.23

7.72e-07

GO:0003677

DNA binding

7 of 996

1.3

1.59

4.10e-06

GO:0003676

Nucleic acid binding

8 of 1926

1.07

1.16

9.65e-06

GO:0008270

Zinc ion binding

3 of 309

1.44

0.79

0.0201

GO:1901363

Heterocyclic compound binding

9 of 5632

0.65

0.52

0.0014

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016591

RNA polymerase II, holoenzyme

10 of 58

2.69

11.09

1.14e-23

GO:0005665

RNA polymerase II, core complex

7 of 16

3.09

9.4

2.39e-18

GO:0005736

RNA polymerase I complex

4 of 13

2.94

4.85

1.03e-09

GO:0005666

RNA polymerase III complex

4 of 19

2.77

4.5

3.61e-09

GO:0005674

Transcription factor TFIIF complex

2 of 2

3.45

2.55

2.53e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5276

RNA Polymerase II Pre-transcription Events, and Tyrosinase activity

10 of 114

2.39

8.72

2.01e-20

CL:5314

RNA polymerase II, core complex

6 of 8

3.33

8.53

2.20e-16

CL:5286

RNA Polymerase II Pre-transcription Events, and Tyrosinase activity

9 of 104

2.39

8.08

1.04e-18

CL:5412

Mixed, incl. Transcription factor TFIIH core complex, and Transcription factor TFIIF complex

3 of 12

2.85

3.12

1.84e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

7 of 55

2.55

7.09

4.23e-15

map03022

Basal transcription factors

3 of 268

1.5

0.97

0.0074

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-76042

RNA Polymerase II Transcription Initiation And Promoter Clearance

10 of 56

2.7

11.17

9.59e-24

MAP-75953

RNA Polymerase II Transcription Initiation

10 of 56

2.7

11.17

9.59e-24

MAP-73779

RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

10 of 56

2.7

11.17

9.59e-24

MAP-73776

RNA Polymerase II Promoter Escape

10 of 56

2.7

11.17

9.59e-24

MAP-77075

RNA Pol II CTD phosphorylation and interaction with CE

9 of 43

2.77

10.66

4.32e-22

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

10 of 99

2.45

9.32

2.08e-21

GOCC:0055029

Nuclear DNA-directed RNA polymerase complex

7 of 74

2.43

6.37

5.24e-14

GOCC:0016591

RNA polymerase II, holoenzyme

6 of 49

2.54

5.9

1.81e-12

GOCC:0005665

RNA polymerase II, core complex

3 of 10

2.93

3.31

8.69e-07

GOCC:0031981

Nuclear lumen

7 of 875

1.35

1.84

4.42e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0804

Transcription

4 of 81

2.14

2.67

3.99e-06

KW-0240

DNA-directed RNA polymerase

3 of 25

2.53

2.61

1.26e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR011039

Transcription Factor IIF, Rap30/Rap74, interaction

2 of 2

3.45

1.48

0.0022

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About